Research Articles
Cracking the Cancer Code: How Dual Targeted Therapy Fights IDH-Mutant Cancers
Explore how combining ATR and PARP inhibitors creates a powerful therapeutic strategy against IDH-mutant cancers through synthetic lethality and DNA damage response targeting.
Unlocking Cancer's Defense System: The Dual Weapon Against Src and Abl Kinases
Discover how N(9)-arenthenyl purines act as dual Src/Abl inhibitors targeting multiple kinase states to combat cancer drug resistance.
New Dimensions in the Biology of Cancer: How 3D Genomics is Revolutionizing Our Fight
Explore how 3D genomics is transforming cancer research by revealing the spatial organization of DNA and its role in gene regulation and cancer development.
Catching Cancer's Fugitives: How Metabolic Clues in Blood Could Revolutionize Lung Cancer Treatment
Exploring how metabolic gene expression in circulating tumor cells from early-stage non-small cell lung cancer patients could transform detection and treatment.
Iron Two Against Cancer: The Promise of Diiron Vinyliminium Complexes
Exploring the potential of diiron vinyliminium complexes as next-generation anticancer agents with novel mechanisms of action.
The Double-Edged Sword: How Oxidation in Tumors Fuels and Fights Cancer
Exploring the paradoxical role of mixed-function oxidation and reactive oxygen species in cancer development and treatment
Disarming the Bodyguard: How a New Strategy Could Make Chemotherapy Work Better
Discover how inhibiting the PI3K/Akt pathway can resensitize gastric cancer to chemotherapy drugs like vincristine, offering new hope for cancer treatment.
A Sweet Solution to a Sour Problem: Can a Candy Root Help Prevent Cancer?
Exploring the chemopreventive potential of 18beta-glycyrrhetinic acid from liquorice root in preventing oral cancer
The Great Escape: How Cancer Cells Evade Our Most Powerful Drugs
Discover how cancer cells use ABCB1 pumps to expel both chemotherapy drugs and their metabolites, creating powerful treatment resistance.
The Guinea Pig's Secret: Unlocking Why Some Animals Resist Cancer
Discover how guinea pigs resist cancer through lysosomal stability - a fascinating look at species differences in chemical carcinogenesis.